How to Take Treatment


RYDAPT® (midostaurin) capsules is a prescription medicine taken by mouth with food. You should always take RYDAPT exactly as your doctor tells you.

How often do I take RYDAPT for advanced systemic mastocytosis (SM)?

RYDAPT dosing RYDAPT dosing RYDAPT dosing

Capsules not actual size.

Your doctor will tell you how many capsules of RYDAPT you need to take. The usual starting dose is 4 capsules twice a day. These should be taken about 12 hours apart (with breakfast and with dinner).

Taking RYDAPT at the same time each day will help you to remember when to take your medicine.

Your doctor may tell you to decrease your dose, temporarily stop, or completely stop taking RYDAPT if you develop certain side effects during treatment with RYDAPT. Do not change your dose unless your doctor tells you to.

Tips for taking RYDAPT

Taking RYDAPTTake RYDAPT exactly as your health care provider tells you

Missing a RYDAPT doseIf you miss a dose of RYDAPT, take your next dose at your scheduled time. Do not take an extra dose to make up for a missed dose

RYDAPT capsulesDo not open or crush RYDAPT capsules

RYDAPT and vomitingIf you vomit after taking a dose of RYDAPT, do not take an extra dose. Take your next dose at your scheduled time. Your doctor may prescribe additional medicines to help with nausea and vomiting, if needed