Understanding Treatment


RYDAPT® (midostaurin) capsules is an oral prescription medicine used to treat adults with advanced systemic mastocytosis (SM). RYDAPT is the only FDA-approved treatment for advanced SM, including those patients with a certain mutation known as the KIT D816V mutation.

How does RYDAPT work?

RYDAPT is thought to work by slowing or stopping the growth of abnormal mast cells in the body. RYDAPT is also thought to block the release of the histamines that may be causing some of the symptoms of advanced SM.

How do I know if RYDAPT is right for me?

RYDAPT is only for patients diagnosed with advanced SM, which includes aggressive systemic mastocytosis (ASM), systemic mastocytosis with associated hematological neoplasm (SM-AHN), and mast cell leukemia (MCL). Talk to your doctor to see if RYDAPT is right for you.