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Understanding Side Effects

RYDAPT

RYDAPT® (midostaurin) capsules may cause side effects. It is important to keep track of the side effects and tell your health care team if they occur.

What are the possible side effects of RYDAPT?

RYDAPT may cause serious side effects, including lung problems. RYDAPT may cause lung problems that may lead to death when used alone or in combination with other chemotherapy medicines. Get medical help right away if you have any new or worsening lung symptoms, including cough, chest discomfort, or shortness of breath.

 

The most common side effects of RYDAPT in people with acute myeloid leukemia (AML) include: low white blood cell counts with fever (febrile neutropenia); nausea; redness, pain, or ulcers on the inside of your mouth (mucositis); vomiting; headache; bruising; muscle or bone pain; nose bleeds; device-related infection; high blood sugar levels (hyperglycemia); and upper respiratory tract infection.

 

Call or inform your health care provider if nausea, vomiting, or diarrhea occurs, gets worse, or does not go away.

 

RYDAPT may cause fertility problems in females and males, which may affect your ability to have children. Talk to your health care provider if you have concerns about fertility.

 

Your health care provider may tell you to decrease your dose, temporarily stop, or completely stop taking RYDAPT if you develop certain side effects during treatment with RYDAPT.

 

Your health care provider will do blood tests to check you for side effects during treatment with RYDAPT.

 

These are not all of the possible side effects of RYDAPT. Call your doctor for medical advice about side effects. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1-800-FDA-1088.